In Preparation / Submitted
In Preparation / Submitted
1. Bagos, P.G., Tsaousis, G.N. and Hamodrakas, S.J. (2009) How many 3D structures do we need to train a predictor? Genomics Proteomics Bioinformatics, 7(3): 128-137. (Impact factor: 6,615 , Citations: 5)
2. Tsaousis, G.N., Tsirigos K.D., Andrianou, X.D., Liakopoulos, T.D., Bagos P.G., Hamodrakas S.J. (2010) ExTopoDB: A database of experimentally derived topological models of transmembrane proteins. Bioinformatics 26(19): 2490–2492. (Impact factor: 4.531, Citations: 21)
3. Kotta-Loizou, I., Tsaousis, G.N., Hamodrakas, S.J. (2013) Analysis of Molecular Recognition Features (MoRFs) in membrane proteins. Biochim Biophys Acta., 15;1834(4): 798-807. (Impact factor: 2,609 , Citations: 27)
4. Gypas, F., Tsaousis, G.N., Hamodrakas, S.J. (2013) mpMoRFsDB: A database of molecular recognition features (MoRFs) in membrane proteins. Bioinformatics doi:10.1093/bioinformatics/btt427. (Impact factor: 4.531, Citations: 8)
5. Tsaousis, G.N., Bagos, P.G. Hamodrakas, S.J. (2014) HMMpTM: Improving transmembrane protein topology prediction using phosphorylation and glycosylation site prediction. Biochim Biophys Acta. 1844(2): 316-322. (Impact factor: 2,609 , Citations: 17)
6. Nastou K.C., Tsaousis G.N., Kremizas K.E., Litou Z.I., Hamodrakas S.J. (2014) The human plasma membrane peripherome: visualization and analysis. BioMed Research International, vol. 2014, Article ID 397145, 12 pages, doi:10.1155/2014/397145. (Impact factor: 2,583 , Citations: 16)
7. Ntostis P., Agiannitopoulos K., Tsaousis G.N., Pantos K., Lamnissou K., (2015) Evidence for association of the rs605059 polymorphism of HSD17B1 gene with recurrent spontaneous abortions. J Matern Fetal Neonatal Med. Dec 4:1-4. (Impact factor: 1,493 , Citations: 6)
8. Nastou K.C., Tsaousis G.N., Papandreou N.C., Hamodrakas S.J. (2016) MBPpred: Proteome-wide detection of membrane lipid-binding proteins using profile Hidden Markov Models. Biochim Biophys Acta 864(7): 747-754 doi: 10.1016/j.bbapap.2016.03.015. (Impact factor: 2,609 , Citations: 7)
9. Papadopoulou E., Metaxa-Mariatou V., Tsaousis G.N., Tsoulos N., Tsirigoti A., Efstathiadou C., Apessos A., Agiannitopoulos K., Pepe G., Bourkoula E., Nasioulas G. (2016) Molecular predictive markers in tumors of the gastrointestinal tract. World J Gastrointest Oncol. 8(11): 772-785 (Impact factor: 2,758 , Citations: 7)
10. Tsoulos N., Papadopoulou E., Metaxa-Mariatou V., Tsaousis G.N., Efstathiadou C., Tounta G., Scapeti A., Bourkoula E., Zarogoulidis P., Pentheroudakis G., Kakolyris S., Boukovinas I., Papakotoulas P., Athanasiadis E., Floros T., Koumarianou A., Barbounis V., Dinischiotu A., Nasioulas G. (2017) Tumor molecular profiling of NSCLC patients using Next Generation Sequencing. Oncol Rep. 38(6):3419-3429. (Impact factor: 3.041, Citations: 22).
11. Apessos Α., Agiannitopoulos Κ., Pepe G., Tsaousis G.N., Papadopoulou E., Mariatou-Metaxa V., Tsirigoti A., Efstathiadou C., Markopoulos C., Xepapadakis G., Venizelos V., Tsiftsoglou A., Natsiopoulos I., Nasioulas G. (2018) Comprehensive BRCA mutation analysis in the Greek population. Experience from a single clinical diagnostic center. Cancer Genet. 220 1–12 (Impact factor: 2,183 , Citations: 9).
12. Tsaousis GN, Papadopoulou E, Apessos A, Agiannitopoulos K, Pepe G, Kambouri S, Diamantopoulos N, Floros T, Iosifidou R, Katopodi O, Koumarianou A, Markopoulos C, Papazisis K, Venizelos V, Xanthakis I, Xepapadakis G, Banu E, Eniu DT, Negru S, Stanculeanu DL, Ungureanu A, Ozmen V, Tansan S, Tekinel M, Yalcin S, Nasioulas G. (2019) Analysis of hereditary cancer syndromes by using a panel of genes: Novel and multiple pathogenic mutations. BMC Cancer. 2019 Jun 3;19(1):535. (Impact factor: 2,933, Citations: 104)
13. Tamposis IA, Tsirigos KD, Theodoropoulou MC, Kontou PI, Tsaousis GN, Sarantopoulou D, Litou ZI, Bagos PG. (2019) JUCHMME: A Java Utility for Class Hidden Markov Models and Extensions for biological sequence analysis. Bioinformatics. Jun 28. pii: btz533. (Impact factor: 4.531, Citations: 1)
14. Agiannitopoulos K., Papadopoulou E., Tsaousis G.N., Pepe G, Kambouri S, Kocdor M.A., Nasioulas G. (2019) Characterization of the c.793-1G>A splicing variant in CHEK2 gene as pathogenic: a case report. BMC Medical Genetics 20, Article number: 131 (Impact factor: 5,481)
15. Papadopoulou E., Tsoulos N., Tsantikidi K., Mariatou-Metaxa V., Stamou P.E., Kladi-Skandali A., Kapeni E., Tsaousis G.N., Pentheroudakis G., Petrakis D., Lampropoulou D.I., Aravantinos G., Varthalitis I., Kesisis G., Boukovinas I., Papakotoulas P., KatirClintzoglou N., Athanasiadis E., Stavridi F., Christodoulou C., Koumarianou A., Eralp Y., Nasioulas G. Clinical Feasibility of NGS liquid biopsy analysis in NSCLC patients. PLoS One. 2019 Dec 20;14(12):e0226853. doi: 10.1371/journal.pone.0226853.
16. Nastou K.C., Tsaousis G.N., Iconomidou V.A. (2020) PerMemDB: a database for eukaryotic peripheral membrane proteins. Biochim Biophys Acta Biomembr. 1;1862(2):183076. (Impact factor: 3,790)
17. Gourgouli K., Gourgouli I., Tsaousis G., Spai S., Efthimiopoulos S., Lamnissou K. (2020) Investigation of genetic base in the treatment of Age-related Macular Degeneration. Int Ophthalmol Jan 8. doi: 10.1007/s10792-019-01274-7.
18. Agiannitopoulos K., Samara P., Papadopoulou M., Efthymiadoy A., Papadopoulou E., Tsaousis G.N.,Mertzanos M., Babalis D., Lamnissou K. (2020) miRNA polymorphisms and risk of premature coronary artery disease. Hellenic Journal of Cardiology doi: 10.1016/j.hjc.2020.01.005
19. Agiannitopoulos K., Papadopoulou E., Tsaousis G.N., Pepe G, Kambouri S, Lypas G. Nasioulas G. (2020) Report of a germline double heterozygote in MSH2 and PALB2. Molecular Genetics & Genomic Medicine doi: 10.1002/mgg3.1242
20. Kontou P., Pavlopoulou A., Dimou N., Pavlopoulos G.A., Theodoropoulou M.C., Braliou G., Tsaousis, G.N., Hamodrakas S.J., Bagos P.G. (2021) The human GPCR signal transduction network. Network Modeling Analysis in Health Informatics and Bioinformatics 10, Article number: 3 doi:10.1007/s13721-020-00278-z.
21. K Agiannitopoulos, G Pepe, E Papadopoulou, Tsaousis G.N., S Kampouri, S Maravelaki, A Fassas, C Christodoulou, R Iosifidou, S Karageorgopoulou, C Markopoulos, I Natsiopoulos, K Papazisis, M Vasilaki-Antonatou, V Venizelos, V Ozmen, S Tansan, K Kaban, DanTudor Eniu, A Chiorean, G Nasioulas (2021) Clinical Utility of Functional RNA Analysis for the Reclassification of Splicing Gene Variants in Hereditary Cancer. Cancer Genomics Proteomics. May-Jun 2021;18(3):285-294. doi: 10.21873/cgp.20259.
22. Özdoğan, M., E. Papadopoulou, N. Tsoulos, A. Tsantikidi, V.-M. Mariatou, G. Tsaousis, E. Kapeni, E. Bourkoula, D. Fotiou, G. Kapetsis, I. Boukovinas, N. Touroutoglou, A. Fassas, A. Adamidis, P. Kosmidis, D. Trafalis, E. Galani, G. Lypas, B. Orhan, S. Tansan, T. Özatlı, O. Kırca, O. Çakır and G. Nasioulas (2021). Comprehensive tumor molecular profile analysis in clinical practice. BMC Medical Genomics 14(1): 105.
23. Tsaousis G.N., Papadopoulou, E., Agiannitopoulos, K., Pepe, G., Tsoulos, N., Boukovinas, I., Floros, T., Iosifidou, R., Katopodi, O., Koumarianou, A., Markopoulos, C., Papazisis, K., Venizelos, V., Kapsimalis, A., Xepapadakis, G., Psyrri, A., Banu, E., Eniu, D.T., Blidaru, A., Stanculeanu, D.L., Ungureanu, A., Ozmen, V., Tansan, S., Tekinel, M., Yalcin, S., Nasioulas, G. (2022) Revisiting the Implications of Positive Germline Testing Results Using Multi-gene Panels in Breast Cancer Patients. Cancer Genomics Proteomics. Jan-Feb 2022;19(1):60-78.
24. Ozmen V., Çağlayan A.O., Ordu C., Erdoğan Z., Aktepe F., Özmen T., İlgün A.S., Öztürk A., Soybir G., Alco G., Pilancı K.N., Elbüken F., Agacayak F., Tapan T.K., Tsaousis G.N., Papadopoulou E., Agiannitopoulos K., Pepe G., Kampouri S., Nasioulas G., Soran A., (2021) Importance of multigene panel test in patients with consanguineous marriage and family history of breast cancer. Oncol Lett 2022 Apr;23(4):118.
25. Apessos A, Agiannitopoulos K, Pepe G, Tsaousis GN, Pitta P, Bili C, Florentin L, Saloustros E, Kampletsas E, Tryfonopoulos D, Tsoukalas N, Bournakis E, Zagouri F, Kotsakis A, Koumarianou A, Korantzis I, Boukovinas I, Lypas G, Fountzilas G, Michalaki V, Xynogalos S, Linardou H, Papadopoulou E, Nasioulas G, Georgoulias V. (2022) Genetic Predisposition to Male Breast Cancer: A Case Series. Anticancer Res. 2022 Dec;42(12):5795-5801. doi: 10.21873/anticanres.16086.
26. Papadopoulou E, Pepe G, Konitsiotis S, Chondrogiorgi M, Grigoriadis N, Kimiskidis VK, Tsivgoulis G, Mitsikostas DD, Chroni E, Domouzoglou E, Tsaousis G, Nasioulas G. (2023) The evolution of comprehensive genetic analysis in neurology: Implications for precision medicine. J Neurol Sci. 2023 Apr 15;447:120609. doi: 10.1016/j.jns.2023.120609. Epub 2023 Mar 5. PMID: 36905813.
27. Agiannitopoulos K, Potska K, Douka A, Gintoni I, Tsaousis GN, Papadopoulou E, Nasioulas G, Yapijakis C. (2023) A novel deletion of exon 4 in the Ectodysplasin A gene associated with X-linked hypohidrotic ectodermal dysplasia. Arch Oral Biol. 2023 Jun;150:105689. doi: 10.1016/j.archoralbio.2023.105689.
28. Bouzarelou D, Agiannitopoulos K, Tsaousis GN, Papadopoulou E, Nasioulas G. Reclassification of Splicing Gene Variants in Hereditary Cancer: Cases Report and Literature Review. In Vivo. 2023 Jul-Aug;37(4):1432-1444. doi: 10.21873/invivo.13227. PMID: 37369490; PMCID: PMC10347938.
29. Agiannitopoulos K, Pepe G, Tsaousis GN, Potska K, Bouzarelou D, Katseli A, Ntogka C, Meintani A, Tsoulos N, Giassas S, Venizelos V, Markopoulos C, Iosifidou R, Karageorgopoulou S, Christodoulou C, Natsiopoulos I, Papazisis K, Vasilaki-Antonatou M, Kabletsas E, Psyrri A, Ziogas D, Lalla E, Koumarianou A, Anastasakou K, Papadimitriou C, Ozmen V, Tansan S, Kaban K, Ozatli T, Eniu DT, Chiorean A, Blidaru A, Rinsma M, Papadopoulou E, Nasioulas G. Copy Number Variations (CNVs) Account for 10.8% of Pathogenic Variants in Patients Referred for Hereditary Cancer Testing. Cancer Genomics Proteomics. 2023 Sep- Oct;20(5):448-455. doi: 10.21873/cgp.20396. PMID: 37643779; PMCID: PMC10464942.
30. Tsantikidi A, Papadopoulou E, Metaxa-Mariatou V, Kapetsis G, Tsaousis G, Meintani A, Florou-Chatzigiannidou C, Gazouli M, Papadimitriou C, Timotheadou E, Kotsakis A, Boutis A, Boukovinas I, Kampletsas E, Kontovinis L, Fountzilas E, Andreadis C, Karanikiotis C, Filippou D, Theodoropoulos G, Özdoğan M, Nasioulas G. The Utility of NGS Analysis in Homologous Recombination Deficiency Tracking. Diagnostics (Basel). 2023 Sep 15;13(18):2962. doi: 10.3390/diagnostics13182962. PMID: 37761329; PMCID: PMC10529941.
31. Agiannitopoulos K, Potska K, Katseli A, Ntogka C, Tsaousis GN, Pepe G, Bouzarelou D, Tsoulos N, Papathanasiou A, Ziogas D, Venizelos V, Markopoulos C, Iosifidou R, Karageorgopoulou S, Giassas S, Natsiopoulos I, Papazisis K, Vasilaki-Antonatou M, Psyrri A, Koumarianou A, Matthaios D, Zairi E, Blidaru A, Banu E, Jinga DC, Laçin Ş, Özdoğan M, Papadopoulou E, Nasioulas G. Only 32.3% of Breast Cancer Families with Pathogenic Variants in Cancer Genes Utilized Cascade Genetic Testing. Cancers (Basel). 2023 Oct 30;15(21):5218. doi: 10.3390/cancers15215218. PMID: 37958392; PMCID: PMC10649031.
32. Tsantikidi A, Papazisis K, Floros T, Gazouli M, Papadopoulou E, Tsaousis G, Nasioulas G, Mester A, Milan KP, Gozman B, Afrasanie V, Stanculeanu DL, Trifanescu O, Pescaru F, Militaru C, Papadimitriou C. RediScore: Prospective validation of a pipeline for homologous recombination deficiency analysis. Oncol Lett. 2023 Sep 22;26(5):480. doi: 10.3892/ol.2023.14060. PMID: 37809048; PMCID: PMC10551864.
33. Fountzilas E, Papadopoulou K, Chatzikonstantinou T, Karakatsoulis G, Constantoulakis P, Tsantikidi A, Tsaousis G, Karageorgopoulou S, Koumarianou A, Mauri D, Ntavatzikos A, Saridaki Z, Petrakis G, Fostira F, Fountzilas G, Liontos M. Concordance between Three Homologous Recombination Deficiency (HRD) Assays in Patients with High-Grade Epithelial Ovarian Cancer. Cancers (Basel). 2023 Nov 22;15(23):5525. doi: 10.3390/cancers15235525. PMID: 38067228; PMCID: PMC10705222.
34. Ziogas DC, Papadopoulou E, Gogas H, Sakellariou S, Felekouras E, Theocharopoulos C, Stefanou DT, Theochari M, Boukovinas I, Matthaios D, Koumarianou A, Zairi E, Liontos M, Koutsoukos K, Metaxa-Mariatou V, Kapetsis G, Meintani A, Tsaousis GN, Nasioulas G. Digging into the NGS Information from a Large-Scale South European Population with Metastatic/Unresectable Pancreatic Ductal Adenocarcinoma: A Real-World Genomic Depiction. Cancers (Basel). 2023 Dec 19;16(1):2. doi: 10.3390/cancers16010002. PMID: 38201431; PMCID: PMC10778112.
35. Papadopoulou E, Rigas G, Fountzilas E, Boutis A, Giassas S, Mitsimponas N, Daliani D, Ziogas DC, Liontos M, Ramfidis V, Christophilakis C, Matthaios D, Floros T, Florou-Chatzigiannidou C, Agiannitopoulos K, Meintani A, Tsantikidi A, Katseli A, Potska K, Tsaousis G, Metaxa-Mariatou V, Nasioulas G. Microsatellite Instability Is Insufficiently Used as a Biomarker for Lynch Syndrome Testing in Clinical Practice. JCO Precis Oncol. 2024 Jan;8:e2300332. doi: 10.1200/PO.23.00332. PMID: 38271656; PMCID: PMC10830089.
36. Agiannitopoulos K, Katseli A, Potska K, Ntogka C, Tsaousis GN, Tsoulos N, Kampoli K, Ntavatzikos A, Papadopoulou E, Nasioulas G, Koumarianou A. Germline Co-deletion of <i>CDKN2A</i> and <i>CDKN2B</i> Genes in Pleomorphic Xanthoastrocytoma: Case Report. In Vivo. 2024 Jul-Aug;38(4):1671-1676. doi: 10.21873/invivo.13617. PMID: 38936911; PMCID: PMC11215628.
37. Tsoulos N, Papadopoulou E, Agiannitopoulos K, Grigoriadis D, Tsaousis GN, Bouzarelou D, Gogas H, Troupis T, Venizelos V, Fountzilas E, Theochari M, Ziogas DC, Giassas S, Koumarianou A, Christopoulou A, Busby G, Nasioulas G, Markopoulos C. Polygenic Risk Score (PRS) Combined with NGS Panel Testing Increases Accuracy in Hereditary Breast Cancer Risk Estimation. Diagnostics (Basel). 2024 Aug 21;14(16):1826. doi: 10.3390/diagnostics14161826. PMID: 39202314; PMCID: PMC11353636.
38. Tsoulos N, Agiannitopoulos K, Potska K, Katseli A, Ntogka C, Pepe G, Bouzarelou D, Papathanasiou A, Grigoriadis D, Tsaousis GN, Gogas H, Troupis T, Papazisis K, Natsiopoulos I, Venizelos V, Amarantidis K, Giassas S, Papadimitriou C, Fountzilas E, Stathoulopoulou M, Koumarianou A, Xepapadakis G, Blidaru A, Zob D, Voinea O, Özdoğan M, Ergören MÇ, Hegmane A, Papadopoulou E, Nasioulas G, Markopoulos C. The Clinical and Genetic Landscape of Hereditary Cancer: Experience from a Single Clinical Diagnostic Laboratory. Cancer Genomics Proteomics. 2024 Sep-Oct;21(5):448-463. doi: 10.21873/cgp.20463. PMID: 39191493; PMCID: PMC11363926.
39. Nikolaidi A, Papadopoulou E, Haidopoulos D, Liontos M, Fountzilas E, Tsaousis G, Goula K, Tsolaki E, Christopoulou A, Binas I, Stamatopoulou S, Koumarianou A, Karageorgopoulou S, Goussia A, Psyrri A, Papadimitriou C, Gogas H. Molecular Alterations in Paired Epithelial Ovarian Tumors in Patients Treated with Neoadjuvant Chemotherapy. Cancers (Basel). 2024 Oct 24;16(21):3580. doi: 10.3390/cancers16213580. PMID: 39518021; PMCID: PMC11545381.
40. Tsaousis G.N., Hamodrakas S.J., Bagos P.G. (2017) Predicting beta barrel transmembrane proteins using HMMs. In: Westhead, D.R., Vijayabaskar, M.S. (Eds.) Hidden Markov Models: Methods and Protocols, Methods in Molecular Biology 1552:43-61. doi:10.1007/978-1-4939-6753-7_4. (Citations: 5).
41. Tsaousis G.N., Theodoropoulou M.C., Hamodrakas S.J., Bagos P.G. (2017) Predicting alpha helical transmembrane proteins using HMMs. In: Westhead, D.R., Vijayabaskar, M.S. (Eds.) Hidden Markov Models: Methods and Protocols, Methods in Molecular Biology 1552:63-82. doi: 10.1007/978-1-4939-6753-7_5. (Citations: 2)